The Smith family is a multigenerational family with a history of hypophosphatemia, a rare genetic disorder characterized by low levels of phosphate in the blood. The pedigree chart below illustrates the inheritance pattern of hypophosphatemia in the Smith family.
Hypophosphatemia is caused by mutations in genes that regulate phosphate metabolism in the body. Inheritance of the disorder can be autosomal dominant or autosomal recessive, depending on the specific gene involved. Symptoms of hypophosphatemia may include muscle weakness, bone pain, and dental problems.
This Is A Pedigree Chart Of A Family With Hypophosphatemia
Interpreting the Pedigree Chart
In the pedigree chart of the Smith family, affected individuals are represented by shaded symbols. The chart shows that hypophosphatemia is inherited in an autosomal dominant manner, as it is passed down from generation to generation. Individuals with the disorder have a 50% chance of passing it on to their offspring.